Aspirin vs Willow Bark
Aspirin derived from willow bark - comparing the modern pharmaceutical with its natural predecessor
Brands: Bayer, Ecotrin, Bufferin
Drug Class
NSAIDEffectiveness Rating
Safety Rating
Mechanism of Action
Irreversibly inhibits COX enzymes, preventing platelet aggregation and reducing inflammation
Common Uses
- Pain relief
- Cardiovascular protection
- Fever reduction
Salix alba
Research Quality
moderateEffectiveness Rating
Safety Rating
Active Compounds
Modern Uses
- Headache
- Lower back pain
- Osteoarthritis
Aspirin is more effective and reliable due to standardization. Willow bark provides milder effects with less predictable dosing.
Both can irritate stomach. Aspirin has more documented risks but also more safety data. Willow bark less studied but traditionally well-tolerated.
Willow bark slightly cheaper but less effective per dose. Aspirin offers better value for consistent results.
Aspirin more convenient with standardized dosing and faster action. Willow bark requires careful preparation and dosing.
Aspirin extensively studied. Willow bark has traditional use and some modern research supporting pain relief effects.
Related Comparisons
Choose aspirin for cardiovascular protection and reliable pain relief. Consider willow bark for mild pain if you prefer whole-plant medicine or have aspirin sensitivity.
⚠️ Medical Disclaimer
This comparison is for informational purposes only. Always consult with a qualified healthcare provider before making decisions about medications or supplements.