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Bupropion

Brand names: Wellbutrin, Zyban

Atypical AntidepressantPrescription Required
Effectiveness
8/10
Safety
7/10
Cost
3/10

How It Works

Inhibits reuptake of norepinephrine and dopamine

Common Uses

  • Depression
  • Seasonal affective disorder
  • Smoking cessation
  • ADHD off-label

Dosage Information

Adults: 150mg once daily initially. May increase to 150mg twice daily or 300mg XL once daily. Take in morning to avoid insomnia.

Common Side Effects

  • Insomnia
  • Dry mouth
  • Headache
  • Nausea
  • Anxiety
  • Weight loss

Important Warnings

  • Increases seizure risk
  • Avoid in eating disorders
  • May increase blood pressure
  • No sexual side effects

Drug Interactions

This medication may interact with the following:

  • MAOIs
  • Other bupropion products
  • Drugs lowering seizure threshold

Medical Disclaimer: This information is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider before making changes to your medication regimen or trying natural alternatives.