Doxepin

Brand names: Silenor

Tricyclic AntidepressantPrescription Required
Effectiveness
8/10
Safety
7/10
Cost
3/10

How It Works

Blocks histamine H1 receptors at low doses producing sedation

Common Uses

  • Insomnia with sleep maintenance difficulty
  • Depression at higher doses

Dosage Information

Adults: 3-6mg once daily within 30 minutes of bedtime. Do not take within 3 hours of a meal.

Common Side Effects

  • Drowsiness
  • Dry mouth
  • Dizziness
  • Weight gain
  • Constipation

Important Warnings

  • Next-day drowsiness possible
  • Avoid alcohol
  • May worsen glaucoma
  • Use caution in elderly

Drug Interactions

This medication may interact with the following:

  • MAOIs
  • SSRIs
  • Cimetidine
  • Anticholinergics

Medical Disclaimer: This information is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider before making changes to your medication regimen or trying natural alternatives.