Trazodone

Brand names: Desyrel

Antidepressant/HypnoticPrescription Required
Effectiveness
7/10
Safety
7/10
Cost
4/10

How It Works

Serotonin antagonist and reuptake inhibitor with sedating properties

Common Uses

  • Insomnia
  • Depression with insomnia
  • Off-label sleep aid

Dosage Information

Adults: 25-100mg at bedtime for insomnia. Higher doses for depression. Take with food to reduce dizziness.

Common Side Effects

  • Drowsiness
  • Dizziness
  • Dry mouth
  • Blurred vision
  • Constipation

Important Warnings

  • May cause priapism
  • Orthostatic hypotension risk
  • Can worsen depression initially
  • Serotonin syndrome risk

Drug Interactions

This medication may interact with the following:

  • MAOIs
  • SSRIs
  • Blood thinners
  • Digoxin
  • Phenytoin

Medical Disclaimer: This information is for educational purposes only and is not intended as medical advice. Always consult with a qualified healthcare provider before making changes to your medication regimen or trying natural alternatives.